Related Experiment Video
Updated: May 1, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
Peripheral ossifying fibroma, some rare findings.
Vivek Chaturvedy1, Amit Kumar Gupta1, Hoti Lal Gupta1
1Department of Periodontology and Oral Implantology, Rajasthan Dental College and Hospital, Jaipur, Rajasthan, India.
Peripheral ossifying fibroma (POF) is a benign gingival growth typically seen in young females. This case highlights a rare occurrence in a male patient, with recurrence and bone erosion noted ten years post-excision.
Area of Science:
- Oral pathology
- Dermatology
- Oncology
Background:
- Peripheral ossifying fibroma (POF) is a common reactive gingival lesion.
- Typically observed in young adults, predominantly females, in the anterior maxilla.
Observation:
- This report details an unusual case of POF in a male patient.
- The lesion recurred ten years after initial surgical excision.
Findings:
- The recurrent lesion exhibited superficial bone erosion.
- Histopathological analysis confirmed the nature of the ossifying fibroma.
Implications:
- This case underscores the importance of long-term follow-up for peripheral ossifying fibromas, even after complete excision.
- Recurrence and bone involvement may occur, necessitating vigilant monitoring in all patients, regardless of demographic factors.
More Related Videos
09:33Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
Published on: August 25, 2023
06:15Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Compact Bone
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Abnormal Proliferation
Abnormal Proliferation
Spongy Bone
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
Gross Anatomy of Bone
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in...