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Microbial learning lessons: SFB educate the immune system
Yun Kyung Lee1, Sarkis K Mazmanian1
1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Abstract:
Segmented filamentous bacteria (SFB) contribute to immune-system maturation. In this issue of Immunity, Goto et al. (2014) and Lécuyer et al. (2014) provide evidence for how SFB induce antigen-specific T helper 17 cells and promote development of adaptive immunity at discrete mucosal sites.
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