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Atypical fibroxanthoma: two unusual variants
P R Wilson1, G M Strutton, M R Stewart
1Department of Dermatology, Royal Brisbane Hospital, Cairns, Australia.
Abstract:
Two unusual fibroxanthomas were studied by light microscopy. The first case contained numerous osteoclast-like cells and resembled malignant giant cell tumour of soft tissues, a variant of malignant fibrous histiocytoma. Osteoclast-like giant cells were negative for lysozyme and alpha-1-antitrypsin. The second case contained areas of chondroid differentiation which resembled chondrosarcoma. Tumour cells within the cartilaginous areas were positive for S100 protein.
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