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Author Spotlight: Development and Characterization of a Mouse Model for Abdominal Aortic Aneurysm
Published on: August 2, 2024
[Treatment strategies of inflammatory abdominal aortic aneurysm]
Minhong Zhang1, Wei Guo1, Xin Du1
1Department of Vascular Surgery, General Hospital of People's Liberation Army, Beijing 100853, China.
Objective:
Summarizes the treatment effect of inflammatory abdominal aortic aneurysm (inflammatory abdominal aortic aneurysm, IAAA), and explore its therapeutic strategy.
Methods:
Retrospectively analysis 17 cases of IAAA in our center from January 2002 to August 2012, 16 males, 1 female, mean age 52-79 (67 ± 8). 4 cases were treated by conservative medical treatment, 5 cases treated by open surgery, 8 cases treated by EVAR.
Results:
During follow-up no aneurysm-related death. Follow-up for the conservative medical treatment group was a mean of (10 ± 6) months, 1 case transit to EVAR, the aneurysm diameter of 2 cases decreased 2 mm and 4 mm, 1 case had no significant diameter change. The mean follow-up time of open group was (28 ± 23) months, mean operation time was (4.9 ± 0.7) hours, Mean operative blood loss was (3 300 ± 370) ml, 1 case with postoperative anastomotic pseudoaneurysm formation. The EVAR group followed up for (20 ± 14) months, without serious perioperative complications, 5 cases aneurysm diameter decreased (5.1 ± 1.5) mm.
Conclusion:
Conservative medical treatment can improve clinical symptoms of IAAA, such as inflammation, abdominal/back pain and hydronephrosis.EVAR is gradually becoming a first-line treatment of IAAA.Open surgery is still the gold standard for treatment of IAAA. Therefore, definite conclusions should be drawn from further studies.
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