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Updated: May 1, 2026
Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
Published on: August 31, 2022
[Comparison analysis of multi-modalities images in 158 patients with hepatic tumor]
Li Huo1, Yonghong Dang1, Ruixue Cui1
1Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Objective:
To compare and analyze the positron emission tomography (PET) images with other multi-modalities in the diagnosis of hepatic tumors.
Methods:
A total of 158 patients undergoing (18)F fluorodeoxyglucose (FDG)-PET were enrolled along with another 55 cases with (11)C acetate-PET (AC-PET) imaging within 1 week. The pathological results were taken as the golden criteria. Tumor marker, contrast ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI) results were collected.SPSS 19.0 was used for statistical analysis.
Results:
Contrast MRI, ultrasound and CT were more effective than PET in the differential diagnosis of hepatic tumor.FDG-PET showed a better accuracy in the diagnosis of intrahepatic cholangiocarcinomas, metastasis and rare primary hepatic carcinoma. AC-PET was a good complementary method to FDG-PET. Consideration of tumor size, amount, laboratory results and history could improve the diagnostic accuracy of PET and enhanced CT.
Conclusion:
PET must be combined with other image modalities to differentiate hepatic tumors more effectively and accurately.
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