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The effect of polymer properties on direct compression and drug release from water-insoluble controlled release

Julia Grund1, Martin Koerber1, Mathias Walther1

  • 1College of Pharmacy, Freie Universität Berlin, Kelchstr. 31, Berlin 12169, Germany.

International Journal of Pharmaceutics
|April 22, 2014
PubMed

Keywords:
Controlled releaseDiprophylline (PubChem CID: 3182)Direct compressionEthocel(®) Std. (PubChem CID: 24832091)Eudragit(®) RS (PubChem CID: 104931)Fumed silica (PubChem CID: 24261)Glass transition temperatureMagnesium stearate (PubChem CID: 11177)Matrix tabletPercolation thresholdPolyvinyl pyrrolidone (PubChem CID: 6917)Water-insoluble polymers

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