Related Experiment Video
Updated: May 1, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
Published on: February 27, 2026
Laryngeal chondrosarcoma diagnosed by core-needle biopsy
Satoru Miyamaru1, Koichi Haba1
1Department of Otolaryngology, Kumamoto City Hospital, Koto, Higashi-ku, Kumamoto, Japan.
Percutaneous core-needle biopsy (CNB) offers a safe and effective method for diagnosing laryngeal chondrosarcoma. This ultrasound-guided technique under local anesthesia provides a less stressful alternative to traditional biopsies.
Area of Science:
- Oncology
- Otolaryngology
- Diagnostic Imaging
Background:
- Laryngeal chondrosarcoma diagnosis typically involves biopsy under general anesthesia, posing challenges for some patients.
- Alternative diagnostic methods are sought due to patient-related physical, economic, and social constraints.
Observation:
- This case report details the successful diagnosis of laryngeal chondrosarcoma using percutaneous core-needle biopsy (CNB) under local anesthesia.
- Ultrasound guidance facilitated tumor detection and sampling, minimizing patient stress.
Findings:
- Percutaneous CNB is presented as a viable and safe diagnostic approach for laryngeal chondrosarcoma.
- Unlike fine-needle aspiration cytology (FNAC), CNB provides tissue for definitive diagnosis, crucial for bone tumors.
- No needle track dissemination, a potential complication, was observed, which is notable for malignant tumors.
Implications:
- This study suggests CNB is a valuable tool for diagnosing primary bone tumors in the head and neck region.
- It advocates for CNB as a less invasive and more accessible diagnostic option compared to laryngomicroscopy.
- The findings encourage wider adoption of CNB for laryngeal chondrosarcoma and similar bone tumors.
Related Concept Videos
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer
Endoscopic Studies II: Thoracocentesis
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Tumor Progression

