Related Experiment Video
Updated: May 1, 2026
10:03
Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
Published on: November 5, 2019
7.0K
Kikuchi disease presenting with aseptic meningitis.
Basem F Khishfe1, Laurie M Krass2, Erik K Nordquist1
1Department of Emergency Medicine, Cook County (Stroger) Hospital, Chicago, IL.
The American Journal of Emergency Medicine
|April 22, 2014
Summary
Kikuchi disease, a rare cause of aseptic meningitis, presents with swollen lymph nodes. Early diagnosis is key for patients with both symptoms, improving patient outcomes.
Area of Science:
- Medicine
- Pathology
- Neurology
Background:
- Kikuchi disease is a rare, self-limiting condition characterized by lymphadenopathy.
- Neurologic complications, such as aseptic meningitis, are uncommon but recognized manifestations.
Observation:
- This case report details a patient presenting with symptoms mimicking aseptic meningitis.
- The patient was ultimately diagnosed with Kikuchi disease.
Findings:
- The report reviews the epidemiology, clinical presentation, and laboratory findings of Kikuchi disease.
- Aseptic meningitis can be an extranodal manifestation of Kikuchi disease.
Implications:
- Considering Kikuchi disease in the differential diagnosis for meningitis is crucial.
- This aids in diagnosing patients who also have regional lymphadenopathy, improving diagnostic accuracy.
Related Concept Videos
01:22Bacterial Meningitis I: Introduction
15
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
15
01:18Viral Meningitis
199
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
199
01:19Encephalitis l: Introduction
15
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
15
01:26Bacterial Meningitis II: Pathophysiology
24
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
24
01:26Brain Abscess l: Introduction
21
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
21
01:25Endocarditis II: Clinical Features of Infective Endocarditis
929
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
929