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Total gastrectomy for gastric carcinoma.

C R Brando1, N B Halpern, J S Aldrete

  • 1Department of Surgery, University of Alabama, Birmingham 35294.

Southern Medical Journal
|August 1, 1989
PubMed
Summary

Total gastrectomy (TG) for advanced gastric cancer shows limited curative potential. Even with curative intent, survival remains poor, highlighting the aggressive nature of these tumors.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Gastroenterology

Background:

  • Gastric carcinoma poses a significant health challenge, particularly when advanced.
  • Total gastrectomy (TG) is a major surgical intervention for advanced gastric cancer.

Purpose of the Study:

  • To evaluate the outcomes of total gastrectomy (TG) for gastric carcinoma.
  • To assess the efficacy and survival rates following TG in patients with advanced disease.

Main Methods:

  • Retrospective analysis of 23 patients who underwent total gastrectomy for gastric carcinoma.
  • Review of TNM staging, histological findings (linitis plastica), complication rates, and survival data.

Main Results:

  • Only 35% of operations were considered curative.
  • 13 complications occurred in 8 patients; no operative deaths.
  • Mean survival was 21.2 months for curative TG versus 10.1 months for palliative TG (P < .001).

Conclusions:

  • Extensive gastric carcinoma involving the fundus/corpus remains highly lethal despite TG.
  • Even curative TG offers limited long-term survival, averaging approximately 21 months.

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