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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
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Related Experiment Video

Updated: May 1, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
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A 3D Organotypic Melanoma Spheroid Skin Model

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Primary anorectal melanoma.

Maliha Khan1, Nora Bucher1, Ahmed Elhassan1

  • 1Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, Ill., USA.

Case Reports in Oncology
|April 22, 2014
PubMed
Summary
This summary is machine-generated.

Primary anorectal malignant melanoma is a rare, aggressive cancer often misdiagnosed, leading to poor prognosis. This case highlights a patient treated with abdominoperineal resection and chemotherapy for advanced disease.

Keywords:
Abdominoperineal resectionChemotherapyPrimary anorectal melanoma

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Area of Science:

  • Gastroenterology
  • Oncology
  • Surgical Pathology

Background:

  • Primary malignant melanoma of the anus and rectum is a rare and aggressive neoplasm.
  • It is often misdiagnosed as hemorrhoids or other benign anorectal conditions, leading to delayed diagnosis and poor prognosis.

Observation:

  • A 71-year-old female presented with painful bowel movements and blood in stools.
  • A mass was found at the anorectal junction with regional lymph node involvement.

Findings:

  • The patient underwent an abdominoperineal resection.
  • The patient is currently scheduled for chemotherapy for advanced disease.

Implications:

  • Early diagnosis and treatment are crucial for improving outcomes in anorectal melanoma.
  • Multidisciplinary treatment approaches, including surgery and chemotherapy, may be necessary for advanced cases.