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Temperature- and pH-dependence of the oxygen-binding reaction of human fetal haemoglobin
M L Doyle1, S J Gill, R De Cristofaro
1Department of Chemistry and Biochemistry, University of Colorado, Boulder 90409-0215.
The Biochemical Journal
|June 1, 1989
Abstract:
O2 binding to human haemoglobin F0 was studied at high haem concentrations (3 mM) in the temperature range 15-35 degrees C and in the pH range 6.8-8.7 at 25 degrees C. Comparison with O2 binding to human adult haemoglobin A0 under identical solution conditions reveals striking similarities in the Bohr effect and the enthalpy of oxygenation between the two haemoglobins.