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Hot spot-based design of small-molecule inhibitors for protein-protein interactions

Wenxing Guo1, John A Wisniewski1, Haitao Ji1

  • 1Department of Chemistry, Center for Cell and Genome Science, University of Utah, 315 South 1400 East, Salt Lake City, UT 84112-0850, USA.

Bioorganic & Medicinal Chemistry Letters
|April 23, 2014
PubMed

Keywords:
Hot spotsInhibitorProtein–protein interactionsRational designSelectivity

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