Sudden death in incident dialysis patients

Related Experiment Video

Updated: May 1, 2026

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

15.0K

Eduardo Vázquez1, Carmen Sánchez-Perales, Francisco García-García

  • 1Department of Cardiology, Complejo Hospitalario de Jaén, Jaén, Spain.

American Journal of Nephrology
|April 23, 2014
PubMed

Insights

Sudden death (SD) is frequent in dialysis patients. Previous myocardial infarction and electrocardiographic abnormalities are key predictors of sudden death within 24 hours and 1 hour of symptom onset.

Area of Science:

  • Nephrology
  • Cardiology
  • Public Health

Background:

  • Sudden death (SD) is a major cause of mortality, particularly in patients with cardiovascular diseases.
  • Dialysis patients face a high prevalence of cardiovascular issues, making SD a significant healthcare concern.

Purpose of the Study:

  • To retrospectively analyze the incidence of sudden death (SD) in patients initiating dialysis.
  • To identify factors associated with the occurrence of SD in this patient population.

Main Methods:

  • A cohort of 285 patients commencing dialysis between November 2003 and September 2007 was evaluated.
  • Follow-up extended until December 2012, recording deaths, transplants, or study completion.
  • Sudden death was defined as occurring within 24 hours (SD 24H) or 1 hour (SD 1H) of symptom onset.

Main Results:

  • Over 947 patient-years, 168 deaths (59%) occurred. 10% experienced SD 24H and 6% experienced SD 1H.
  • Multivariate analysis identified prior myocardial infarction and electrocardiographic abnormalities (Q wave, negative T wave, subendocardial lesion, QRS >120 ms) as independent predictors.
  • These factors significantly increased the odds of SD 24H (OR 7.83) and SD 1H (OR 13.43).

Conclusions:

  • Sudden death is a frequent event in patients undergoing dialysis.
  • Distinct patient groups with clearly differentiated risk profiles for sudden death can be identified.
Abstract

More Related Videos

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis04:36

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis

Published on: October 2, 2020

2.3K
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

4.1K

Related Concept Videos

Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
2.2K
Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
2.2K
Dialysis01:15

Dialysis

Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
2.1K
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
527
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
1.4K
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
4.0K