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Related Concept Videos

Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

20
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins...
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Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

19
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this...
19
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

30
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
30
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

20
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
20
Brain Imaging01:14

Brain Imaging

1.0K
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
1.0K
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

27
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component...
27

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Related Experiment Video

Updated: May 1, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Migraine and structural abnormalities in the brain.

Anders Hougaard1, Faisal Mohammad Amin, Messoud Ashina

  • 1Danish Headache Center and Department of Neurology, Glostrup Hospital, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

Current Opinion in Neurology
|April 23, 2014
PubMed
Summary
This summary is machine-generated.

Migraine may cause brain structure changes, particularly white matter abnormalities and silent infarct-like lesions. While not linked to cognitive decline, these changes might increase stroke risk, especially in migraine with aura patients.

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Area of Science:

  • Neurology
  • Neuroimaging

Background:

  • Migraine research extensively investigates brain structure.
  • Advances in neuroimaging are crucial for understanding these changes.

Purpose of the Study:

  • To review recent studies on structural brain abnormalities in migraine.
  • To discuss the clinical significance of these findings.

Main Methods:

  • Review of recent population-based studies and neuroimaging research.
  • Analysis of structural brain changes in migraine patients.

Main Results:

  • Evidence suggests an increased prevalence of white matter abnormalities and silent infarct-like lesions in migraine.
  • Grey matter changes in migraine remain unclear.
  • Structural changes are not associated with cognitive decline.

Conclusions:

  • Migraine may be a risk factor for brain structural changes.
  • A potential link exists between these changes and increased stroke risk, particularly in migraine with aura.
  • Further longitudinal studies are needed to clarify the impact of migraine subtype, attack frequency, and sex.
  • Brain structure changes could serve as biomarkers for patient stratification and prognosis.