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Updated: May 1, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
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Cardiovascular comorbidities in childhood psoriasis
Tiago Torres1, Susana Machado2, Denisa Mendonça3
1Department of Dermatology, Centro Hospitalar do Porto, Ex. CICAP, Rua D. Manuel II, s/n, 4100 Porto, Portugal, Unit for Multidisciplinary Investigation in Biomedicine.
European Journal of Dermatology : EJD
|April 23, 2014
Summary
Children with psoriasis show higher rates of excess adiposity and cardiovascular risks, similar to adults. This highlights the need for early screening and lifestyle interventions in pediatric psoriasis patients.
Area of Science:
- Pediatric dermatology
- Cardiovascular health in children
- Systemic inflammatory diseases
Background:
- Psoriasis is a chronic inflammatory skin disease linked to cardiovascular issues in adults.
- Limited data exists on these comorbidities in childhood psoriasis.
Purpose of the Study:
- To assess excess adiposity, cardiovascular risk factors, metabolic syndrome, and lipid profiles in children with psoriasis.
- Compare these parameters between psoriatic children and a control group.
Main Methods:
- A case-control study involving children aged 5-15 with moderate-to-severe plaque psoriasis.
- A control group of children with non-systemic inflammatory skin conditions was included.
Main Results:
- Psoriatic children had significantly higher odds of excess adiposity (BMI, waist circumference, waist-to-height ratio).
- Metabolic syndrome prevalence was higher in psoriatic children (25% vs 3.7%), with significantly increased waist circumference and high blood pressure.
- Psoriatic patients without excess adiposity exhibited an altered, more atherogenic lipid profile.
Conclusions:
- Cardiovascular comorbidities associated with adult psoriasis are present in childhood psoriasis.
- Screening for cardiovascular comorbidities and promoting healthy lifestyles are crucial for children with psoriasis.
- The link between psoriasis and these conditions may have a genetic component.
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