Factors influencing tone in rabbit large intestine

Pressure/volume curves obtained in the presence of papaverine have been compared with those obtained under control conditions in rabbit large intestine. Tension/length curves obtained on stimulation of the extrinsic nerve supply to the intestine have been compared with control curves. Evidence is presented for a small contribution of sustained muscular activity to the pressue/volume and tension/length curves. The effect of stretch on peak tension attained by the intestine has also been examined.