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Nuchal Translucency Quality Review (NTQR) program: first one and half million results
H Cuckle1, L D Platt, L L Thornburg
1Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY, USA.
Summary
First-trimester nuchal translucency (NT) measurement quality varies among providers despite training. More experienced professionals demonstrated better accuracy in NT assessments, indicating a need for continued quality improvement in prenatal screening programs.
Area of Science:
- Medical Imaging
- Prenatal Diagnostics
- Quality Assurance
Background:
- First-trimester nuchal translucency (NT) measurement is a critical component of prenatal screening for chromosomal abnormalities.
- The Nuchal Translucency Quality Review (NTQR) program aims to standardize and improve the quality of NT measurements.
- Provider performance in NT measurement can significantly impact screening accuracy.
Purpose of the Study:
- To evaluate the performance of first-trimester nuchal translucency (NT) measurement providers within the NTQR program.
- To identify factors influencing variability in NT measurement performance among physician-sonologists and sonographers.
Main Methods:
- The NTQR program monitored provider performance using median multiple of the normal median (MoM) for crown-rump length (CRL) within a 0.9-1.1 MoM range.
- Standard deviation (SD) of log10 MoM and regression slope of NT on CRL were also assessed.
- Performance indicators were analyzed across 4710 providers and 2150 ultrasound units.
Main Results:
- Among 1,485,944 scans, the median provider NT-MoM was 0.913, with only 55% achieving the target range.
- A tendency towards under-measurement was observed, with significant variations in NT-MoM, SD, and slope among providers.
- Provider experience, including time in the NTQR program and annual scan volume, correlated with improved performance.
Conclusions:
- Considerable variability in NT measurement performance persists among providers, even with extensive training and credentialing.
- Experienced providers demonstrated performance closer to expected values, suggesting a learning curve effect.
- Continuous quality monitoring and targeted interventions are necessary to minimize performance variations and enhance screening accuracy.

