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Evidence for a myotropic effect of substance P in Periplaneta americana L
H Penzlin1, I Wieduwilt, W Hertel
1Department of Animal Physiology, Friedrich-Schiller-University of Jena, German Democratic Republic.
General and Comparative Endocrinology
|July 1, 1989
Abstract:
It is shown that the isolated oviduct as well as the proctodeum of the cockroach Periplaneta americana are sensitive to substance P application. In contrast, the hyperneural muscle and the dilator muscle of the antennal heart were insensitive to this neuropeptide. The entire substance P amino acid sequence is necessary for the effects. This provides evidence for a pharmacological effect of substance P in insects.
