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Updated: Aug 18, 2026

Preparing T Cell Growth Factor from Rat Splenocytes
Published on: October 31, 2007
[Therapeutic plasmapheresis using a cell separator]
N N Kalinin1, M M Petrov, V J Petrova
1Zentralinstitut für Hämatologie und Bluttransfusion Moskau, UdSSR.
For the purpose of improving disturbances of the immunosystem 188 plasmaphereses were carried out in 64 patients. This reports deals with the results of 85 therapeutic plasmaphereses in 39 patients with rheumatoid arthritis, diabetes mellitus, and neurodermatitis or pregnant women with rhesus antibodies for diminishing antibody titres. The Soviet equipment of the type RK-0.5, PF-0.5 and FK-3.5 as well as the US devices Aminco and IBM were used. A decrease of the serum protein content from 9-13% appeared immediately after plasmaphereses with 1.3 l of plasma withdrawal per week and an average substitution of 40% of the protein loss by using a 5% solution of albumin. A continual control of this parameter is necessary.
For the purpose of improving disturbances of the immunosystem 188 plasmaphereses were carried out in 64 patients. This reports deals with the results of 85 therapeutic plasmaphereses in 39 patients with rheumatoid arthritis, diabetes mellitus, and neurodermatitis or pregnant women with rhesus antibodies for diminishing antibody titres. The Soviet equipment of the type RK-0.5, PF-0.5 and FK-3.5 as well as the US devices Aminco and IBM were used. A decrease of the serum protein content from 9-13% appeared immediately after plasmaphereses with 1.3 l of plasma withdrawal per week and an average substitution of 40% of the protein loss by using a 5% solution of albumin. A continual control of this parameter is necessary.
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