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Related Concept Videos

Birth Control Methods01:22

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Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
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The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
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Intrauterine Drug Delivery Systems01:21

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Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
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The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
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Hormonal Regulation01:33

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The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
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Hormonal Regulation01:40

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Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
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Updated: May 1, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
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Hormonal anticonception anno 2013: a clinician's view.

M Dhont1, V Verhaeghe1

  • 1Department of Obstetrics and Gynaecology, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium.

Facts, Views & Vision in Obgyn
|April 23, 2014
PubMed
Summary

New data on thrombosis risk with hormonal contraception is prompting guideline reviews. This summary offers a clinician

Area of Science:

  • Reproductive Health
  • Pharmacovigilance
  • Thrombosis Research

Background:

  • Recent data links hormonal contraception to increased risk of venous and arterial thrombosis.
  • This contrasts with the 1996 'pill scare' regarding second- vs. third-generation pills.
  • Newer progestogens in hormonal contraceptives are under scrutiny for thrombotic risk.

Purpose of the Study:

  • To summarize current evidence on thrombotic risks associated with hormonal contraceptives.
  • To provide a clinician's perspective on indications and contraindications for hormonal contraception.
  • To contextualize hormonal contraceptive use within its non-contraceptive health benefits.

Main Methods:

  • Review of emerging scientific evidence on hormonal contraceptive-associated thrombosis.
Keywords:
Contraceptionclinicalcurrent opinionhormonalsafetyside-effects

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  • Analysis of clinical guidelines and recommendations.
  • Synthesis of data from a clinician's viewpoint.

    • Main Results:

    • Evidence regarding thrombotic risk with newer progestogens is accumulating.
    • A re-evaluation of current guidelines for hormonal contraception is underway.
    • Hormonal contraceptives offer significant non-contraceptive health benefits.

    Conclusions:

    • The evolving understanding of thrombosis risk necessitates updated clinical guidance for hormonal contraception.
    • Balancing risks and benefits, including non-contraceptive advantages, is crucial for prescribing.
    • Continued vigilance and evidence synthesis are essential for safe hormonal contraceptive use.