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Hormonal anticonception anno 2013: a clinician's view.
1Department of Obstetrics and Gynaecology, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium.
Facts, Views & Vision in Obgyn
|April 23, 2014
Summary
New data on thrombosis risk with hormonal contraception is prompting guideline reviews. This summary offers a clinician
Area of Science:
- Reproductive Health
- Pharmacovigilance
- Thrombosis Research
Background:
- Recent data links hormonal contraception to increased risk of venous and arterial thrombosis.
- This contrasts with the 1996 'pill scare' regarding second- vs. third-generation pills.
- Newer progestogens in hormonal contraceptives are under scrutiny for thrombotic risk.
Purpose of the Study:
- To summarize current evidence on thrombotic risks associated with hormonal contraceptives.
- To provide a clinician's perspective on indications and contraindications for hormonal contraception.
- To contextualize hormonal contraceptive use within its non-contraceptive health benefits.
Main Methods:
- Review of emerging scientific evidence on hormonal contraceptive-associated thrombosis.
- Analysis of clinical guidelines and recommendations.
- Synthesis of data from a clinician's viewpoint.
Main Results:
- Evidence regarding thrombotic risk with newer progestogens is accumulating.
- A re-evaluation of current guidelines for hormonal contraception is underway.
- Hormonal contraceptives offer significant non-contraceptive health benefits.
Conclusions:
- The evolving understanding of thrombosis risk necessitates updated clinical guidance for hormonal contraception.
- Balancing risks and benefits, including non-contraceptive advantages, is crucial for prescribing.
- Continued vigilance and evidence synthesis are essential for safe hormonal contraceptive use.
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