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Related Experiment Video

Updated: Apr 30, 2026

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

Published on: September 26, 2019

Bacterial collagenases - A review.

Ana Sofia Duarte¹, Antonio Correia¹, Ana Cristina Esteves¹

¹a Department of Biology and Cesam , University of Aveiro, Campus Universitario de Santiago , Aveiro , Portugal.

Critical Reviews in Microbiology

|April 24, 2014

Summary

This summary is machine-generated.

Bacterial collagenases, crucial for virulence and biotechnological applications, lack a standardized classification. This review provides recent data and proposes a new guide for classifying these metalloproteinases.

Keywords:

Collagen Dupuytren disease M9-peptidases metalloproteinases microbial collagenases

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Last Updated: Apr 30, 2026

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

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One-step Extraction and Zymographic Analysis of Bacterial Gelatinases

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Area of Science:

Microbiology
Biochemistry
Enzymology

Background:

Bacterial collagenases are metalloproteinases that degrade extracellular matrices, acting as key virulence factors in pathogenic bacteria.
Existing scientific classification and identification of bacterial collagenases are inconsistent, leading to controversy.
Clostridial collagenases serve as benchmarks for characterizing newly discovered collagenolytic enzymes.

Purpose of the Study:

To present recent data on bacterial collagenases.
To provide an overview of their functional, structural, and molecular diversity.
To propose a new classification system for bacterial collagenases.

Main Methods:

Literature review of recent data on bacterial collagenases.
Analysis of functional, structural, and molecular diversity.
Development of a novel classification guide.

Main Results:

Recent advancements in understanding bacterial collagenases are detailed.
The molecular diversity and distribution of these enzymes are elucidated.
A new classification guide for bacterial collagenases is proposed.

Conclusions:

A comprehensive overview of bacterial collagenases, including their diversity and applications, is provided.
The proposed classification guide aims to resolve inconsistencies and facilitate straightforward identification.
This work supports advancements in biotechnology and therapeutics through better enzyme characterization.