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Phenolic constituents from the roots of Phyllodium pulchellum
Yang Zong1, Ming Zhong, Dong-Mei Li
1a College of Pharmacy, Dalian Medical University , Dalian 116044 , China.
Abstract:
Three new phenolic constituents 1-3 were obtained from the 95% ethanol extract of the roots of Phyllodium pulchellum (Leguminosae). Their structures were elucidated on the basis of spectroscopic analyses, such as NMR, UV, IR, HR-ESI-MS, and CD. Furthermore, in an in vitro bioassay, all compounds were tested for inhibitory effects against the proliferation of acetaldehyde-stimulated HSC-T6 cells, and compound 3 exhibited potent inhibitory activity with the IC50 value of 7.6 μM.
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