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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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[Pregnancy and fertility in schizophrenia]

Koen P Grootens1

  • 1Reinier van Arkel groep, locatie Jeroen Bosch Ziekenhuis, 's-Hertogenbosch.

Nederlands Tijdschrift Voor Geneeskunde
|April 24, 2014
PubMed

Pregnancy and childbirth are risky periods for developing psychotic dysregulation in patients with schizophrenia. Antipsychotic treatment significantly reduces the risk, but also implies possible adverse effects on the neonate, such as neonatal adaptation symptoms and a slightly increased risk of congenital defects. Patients with schizophrenia are at higher risk of obstetric complications. Optimal care for these patients requires coordination between multiple disciplines. Timely counselling with the patient on lifestyle, sexual side effects and contraception yields many health benefits.

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