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Primary diffuse large B-cell lymphoma of the chest wall: a case report
Xiaoming Qiu, Yi Liu, Yanjie Qiao
1Department of Lung Cancer Surgery, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, No 154, Anshan Road, Heping District, 30052 Tianjin, People's Republic of China. huntercj2004@yahoo.com.
World Journal of Surgical Oncology
|April 24, 2014
Summary
Primary diffuse large B-cell lymphoma of the chest wall is exceptionally rare. This report details a case in a 62-year-old woman, highlighting diagnosis and treatment of this unusual thoracic malignancy.
Area of Science:
- Oncology
- Pathology
- Thoracic Surgery
Background:
- Primary diffuse large B-cell lymphoma (DLBCL) is a common non-Hodgkin lymphoma, but extranodal involvement of the chest wall is exceedingly rare.
- Chest wall tumors can present with diverse etiologies, necessitating thorough diagnostic evaluation.
Observation:
- A 62-year-old Chinese woman presented with left-sided chest pain.
- Computed tomography revealed a solid, round mass in the left anterior chest wall, affecting the second and third costal cartilages.
Findings:
- The resected mass exhibited histological and immunohistochemical features consistent with primary diffuse large B-cell lymphoma.
- Surgical resection and chest wall reconstruction were successfully performed.
Implications:
- This case underscores the importance of considering rare diagnoses like primary DLBCL of the chest wall in patients with unexplained thoracic masses.
- Accurate diagnosis through histology and immunohistochemistry is crucial for appropriate management and treatment planning.
- Complete surgical resection followed by reconstruction can be a viable therapeutic approach for localized primary chest wall lymphoma.
