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Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images
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Cortical microinfarcts on 7T MRI in patients with spontaneous intracerebral hemorrhage

Susanne J van Veluw1, Wilmar M T Jolink1, Jeroen Hendrikse2

  • 1Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
|April 24, 2014
PubMed

Insights

Cortical cerebral microinfarcts are common in patients with spontaneous intracerebral hemorrhage (ICH). This finding suggests microinfarcts may indicate underlying small vessel disease in ICH patients.

Area of Science:

  • Neurology
  • Radiology
  • Vascular Medicine

Background:

  • Coexisting brain imaging abnormalities in spontaneous intracerebral hemorrhage (ICH) can suggest underlying small vessel disease.
  • Cortical cerebral microinfarcts are potential markers of vascular damage.

Purpose of the Study:

  • To investigate cortical cerebral microinfarcts as a novel marker of vascular damage in patients with spontaneous ICH.
  • To determine the prevalence of microinfarcts in ICH patients compared to controls.

Main Methods:

  • Utilized 7Tesla magnetic resonance imaging (MRI) for detailed brain imaging.
  • Included twelve patients diagnosed with spontaneous ICH and fifteen healthy controls.

Main Results:

  • Microinfarcts were identified in 9 out of 12 (75%) patients with spontaneous ICH.
  • Microinfarcts were also present in 5 out of 15 (33%) control subjects.
  • This suggests microinfarcts are a common comorbidity in spontaneous ICH.

Conclusions:

  • Cortical cerebral microinfarcts are frequently observed in patients with spontaneous ICH.
  • These findings highlight microinfarcts as a potential indicator of vascular comorbidities in ICH.
  • Further research with larger cohorts is needed to confirm the etiological significance of microinfarcts in ICH.

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