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Updated: Apr 30, 2026

Chemical Modification of the Tryptophan Residue in a Recombinant Ca2+-ATPase N-domain for Studying Tryptophan-ANS FRET
Published on: October 9, 2021
A tetranaphthoimidazolium receptor as a fluorescent chemosensor for phytate
Minji Lee1, Jong Hun Moon, Eun Jin Jun
1Department of Chemistry and Nano Science, Global Top5 Research Program, Ewha Womans University, Seoul 120-750, Korea. jyoon@ewha.ac.kr.
Abstract:
A new tetranaphthoimidazolium receptor was synthesized and reported to be a selective fluorescent chemosensor for phytate, myo-inositol hexakisphosphate (IP6). In a 100% aqueous solution at pH 7.4, chemosensor 1 showed a selective fluorescence enhancement for IP6 over IP3, phosphates, pyrophosphates, AMP, ADP and ATP. An excimer emission at 465 nm linearly increases in the range of 300 nM to 1 μM with a detection limit of 2.28 × 10(-7) M. In addition, first live cell imaging of IP6 has been demonstrated by using a synthetic receptor.

