Cancers Originate from Somatic Mutations in a Single Cell
Tumor Progression
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Updated: Apr 30, 2026

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
Published on: January 14, 2014
Yong-Su Jung1, Se-Hoon Kim1, Sung-Kon Ha1
1Department of Neurosurgery, Ansan Hospital, Korea University School of Medicine, Ansan, Republic of Korea.
This case study highlights a rare instance of a triple primary origin tumor. Pathologic confirmation is crucial for accurate diagnosis and treatment, even with a history of other cancers.
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