Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aryldiazonium Salts to Azo Dyes: Diazo Coupling01:11

Aryldiazonium Salts to Azo Dyes: Diazo Coupling

3.2K
The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...
3.2K
Diazonium Group Substitution with Halogens and Cyanide: Sandmeyer and Schiemann Reactions01:20

Diazonium Group Substitution with Halogens and Cyanide: Sandmeyer and Schiemann Reactions

2.0K
Arenediazonium substitution reactions occur when the diazonium group is substituted by various functional groups such as halides, hydroxyl, nitrile, etc. For instance, arenediazonium salts react with copper(I) salts of chloride, bromide, or cyanide to form corresponding aryl chlorides, bromides, and nitriles. These reactions are named Sandmeyer reactions. Although the mechanism of this reaction is complicated, as illustrated in Figure 1, they are believed to progress via an aryl copper...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

VOCs Adsorption and Exchange Properties in Bispidine-Based Mn(II) 1D CPs Made of Orthogonally Oriented Linear Chains.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same author

Interrelationships Among Physical Fitness, General Motor Coordination, and Soccer-Specific Technical Skills in Youth Soccer Players.

Sports (Basel, Switzerland)·2026
Same author

Employment of the fluorescent probe hydroxy-naphthyl-methylbenzoxazole-based dye and its combination with fluorescent silica nanoparticles as potential heavy metal-targeting systems: results and troubleshooting in Cd-polluted environments.

Analytical and bioanalytical chemistry·2026
Same author

Synthesis and Characterization of a Novel Biphenol-Based Gadolinium Complex for Encapsulation in Human Red Blood Cells.

International journal of molecular sciences·2026
Same author

Expanding the Coordination Chemistry of Decavanadate through π-Hole Interactions with Transition-Metal Cyclen Complexes: Electronic Features and Dye Adsorption.

Inorganic chemistry·2026
Same author

Evaluation of the hepatitis c virus screening program in the Marche Region (Italy): experience from the Pesaro-Urbino health authority.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2026

Related Experiment Video

Updated: Apr 30, 2026

A Modular Microfluidic Technology for Systematic Studies of Colloidal Semiconductor Nanocrystals
09:58

A Modular Microfluidic Technology for Systematic Studies of Colloidal Semiconductor Nanocrystals

Published on: May 10, 2018

9.0K

Modulating the sensor response to halide using NBD-based azamacrocycles.

Stefano Amatori1, Gianluca Ambrosi, Elisa Borgogelli

  • 1Department of Base Sciences and Fundamentals, Chemistry Section, University of Urbino "Carlo Bo" , P.zza Rinascimento 6, I-61029 Urbino, Italy.

Inorganic Chemistry
|April 25, 2014
PubMed
Summary

This study introduces Ligand L, a fluorescent sensor for detecting metal ions like Cu(II), Zn(II), and Cd(II). The sensor can also detect halide anions and exhibits fluorescence within cells.

More Related Videos

Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms
08:28

Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms

Published on: March 3, 2023

1.9K
Multi-analyte Biochip MAB Based on All-solid-state Ion-selective Electrodes ASSISE for Physiological Research
08:03

Multi-analyte Biochip MAB Based on All-solid-state Ion-selective Electrodes ASSISE for Physiological Research

Published on: April 18, 2013

16.7K

Related Experiment Videos

Last Updated: Apr 30, 2026

A Modular Microfluidic Technology for Systematic Studies of Colloidal Semiconductor Nanocrystals
09:58

A Modular Microfluidic Technology for Systematic Studies of Colloidal Semiconductor Nanocrystals

Published on: May 10, 2018

9.0K
Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms
08:28

Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms

Published on: March 3, 2023

1.9K
Multi-analyte Biochip MAB Based on All-solid-state Ion-selective Electrodes ASSISE for Physiological Research
08:03

Multi-analyte Biochip MAB Based on All-solid-state Ion-selective Electrodes ASSISE for Physiological Research

Published on: April 18, 2013

16.7K

Area of Science:

  • Coordination Chemistry
  • Supramolecular Chemistry
  • Chemical Sensing

Background:

  • Ligand L, a novel fluorescent sensor, is designed for metal ion detection.
  • The sensor exhibits cell permeability and intracellular fluorescence.
  • Metal complexes of Ligand L can potentially detect halide anions.

Purpose of the Study:

  • To investigate the coordination behavior of Ligand L with Cu(II), Zn(II), and Cd(II) ions.
  • To explore the sensing capabilities of Ligand L and its metal complexes towards metal ions and anions.
  • To elucidate the structural and photophysical properties of the formed complexes.

Main Methods:

  • Synthesis and characterization of Ligand L.
  • Formation and spectroscopic analysis of metal complexes with Cu(II), Zn(II), and Cd(II).
  • Investigation of the sensing properties towards metal ions and halide anions.
  • X-ray crystallography for structural determination of a cadmium complex.

Main Results:

  • Ligand L forms dinuclear complexes with Cu(II), Zn(II), and Cd(II) with a [M(2)H(-1)L]3+ stoichiometry.
  • A CHEF (Chelation-Enhanced Fluorescence) effect is observed upon metal coordination.
  • The Zn(II) complex acts as an OFF-ON sensor for fluoride and chloride anions.
  • The crystal structure of a dinuclear cadmium complex was determined.

Conclusions:

  • Ligand L is a versatile fluorescent sensor for specific metal ions and halide anions.
  • The metal complexes exhibit interesting coordination behavior and sensing capabilities.
  • The study provides insights into the design of fluorescent sensors for complex biological and environmental samples.