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Identification and Dissection of Diverse Mouse Adipose Depots
Published on: July 11, 2019
Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus
Odunayo Ibraheem Azeez1, Roy Meintjes, Joseph Panashe Chamunorwa
1Department of Anatomy and Physiology, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110 Pretoria, South Africa. odunayoazeez@yahoo.com.
Abstract:
The fat body in invertebrates was shown to participate in energy storage and homeostasis, apart from its other roles in immune mediation and protein synthesis to mention a few. Thus, sharing similar characteristics with the liver and adipose tissues in vertebrates. However, vertebrate adipose tissue or fat has been incriminated in the pathophysiology of metabolic disorders due to its role in production of pro-inflammatory cytokines. This has not been reported in the insect fat body. The link between the fat body and adipose tissue was examined in this review with the aim of determining the principal factors responsible for resistance to inflammation in the insect fat body. This could be the missing link in the prevention of metabolic disorders in vertebrates, occasioned by obesity.
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