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Current Issues in the Management of Pediatric Functional Abdominal Pain
Claudio Romano1, Federica Porcaro
1Pediatric Department, University of Messina, Italy. romanoc@unime.it.
Insights
Chronic abdominal pain (CAP) affects 12% of children, impacting their quality of life. This review updates diagnostic criteria and management for pediatric CAP, a condition linked to brain-gut axis dysfunction.
Area of Science:
- Pediatric Gastroenterology
- Functional Gastrointestinal Disorders
- Neurogastroenterology
Background:
- Chronic abdominal pain (CAP) is a prevalent functional gastrointestinal disorder (FGID) in children (2-18 years), affecting 12% of this population.
- CAP is hypothesized to stem from brain-gut axis dysfunction, influenced by biological, psychological, and social factors.
- Children with CAP experience reduced quality of life, comparable to those with organic conditions like inflammatory bowel disease.
Purpose of the Study:
- To update diagnostic criteria for pediatric chronic abdominal pain.
- To provide guidance on follow-up and treatment strategies for pediatric CAP.
- To emphasize the importance of the Rome III criteria for clinical diagnosis.
Main Methods:
- Review of updated diagnostic criteria for pediatric functional abdominal pain.
- Analysis of factors contributing to the brain-gut axis dysfunction in CAP.
- Discussion of treatment and follow-up protocols for children with CAP.
Main Results:
- CAP significantly impairs quality of life in children.
- Approximately 30% of pediatric CAP cases persist, posing a risk for adult irritable bowel syndrome.
- Standardized diagnostic criteria and appropriate follow-up are crucial for effective management.
Conclusions:
- Updated diagnostic criteria and management strategies are essential for pediatric CAP.
- Early and accurate diagnosis using tools like Rome III criteria can improve patient outcomes.
- Further research is needed to understand the economic impact of pediatric CAP.
Abstract:
Chronic abdominal pain (CAP) is a prevalent disorder related to functional gastrointestinal disorders (FGIDs). In pediatric setting, CAP is a common presenting problem among children and adolescents ages 2 to 18 years with a median prevalence rate of 12%. It was proposed that CAP is the result of the altered pain sensation due to a dysfunction of the brain-gut axis after a complex interaction among biological, psychological and social factors. Children with CAP experience decrease in quality of life compared to children with identifiable organic disease such as inflammatory bowel disease. Despite treatment, 30% of children with CAP have long-lasting complaints with evidence that CAP is a risk factor for the occurrence of irritable bowel syndrome in adults. Efforts have subsequently been made to standardize the diagnostic criteria and adequate follow-up. CAP is associated with significative impairment with considerable impact on self-reported quality of life. The direct and indirect costs are not known in pediatric population and the access to investigations it's frequent. A more appropriate use of Rome III criteria would allow for a clinical diagnosis. The focus of this article will be to report the updated criteria for the diagnosis, follow-up and treatment of this condition.
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