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Updated: Apr 30, 2026

Measurement of Basal and Forskolin-stimulated Lipolysis in Inguinal Adipose Fat Pads
Published on: July 21, 2017
Panax red ginseng extract regulates energy expenditures by modulating PKA dependent lipid mobilization in adipose
Hae-Mi Cho1, Young-Ho Kang1, Hanju Yoo1
1Department of Biomedical Sciences, Cell Dysfunction Research Center (CDRC), University of Ulsan, College of Medicine, Seoul 138-736, Republic of Korea.
Abstract:
Regulation of balance between lipid accumulation and energy consumption is a critical step for the maintenance of energy homeostasis. Here, we show that Panax red ginseng extract treatments increased energy expenditures and prevented mice from diet induced obesity. Panax red ginseng extracts strongly activated Hormone Specific Lipase (HSL) via Protein Kinase A (PKA). Since activation of HSL induces lipolysis in WAT and fatty acid oxidation in brown adipose tissue (BAT), these results suggest that Panax red ginseng extracts reduce HFD induced obesity by regulating lipid mobilization.
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