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Updated: Apr 30, 2026

Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Coronary Revascularization Using Bilateral Internal Thoracic Arteries: Safe with Skeletonization?
Brody Wehman1, Bradley Taylor1
1Division of Cardiac Surgery, University of Maryland Medical Center, Baltimore, MD, USA.
Insights
Bilateral internal thoracic artery (BITA) grafting offers long-term survival benefits in coronary artery bypass grafting but is underused. Skeletonization technique may reduce sternal wound infection risk with BITA use.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Surgical Innovation
Background:
- Bilateral internal thoracic artery (BITA) grafting is associated with superior long-term survival in coronary artery bypass grafting (CABG).
- Despite evidence, BITA utilization remains low, particularly in the United States.
- Sternal wound complications are a concern with BITA grafting.
Purpose of the Study:
- To review the evidence supporting the benefits of BITA grafting.
- To examine the risks of sternal wound complications associated with BITA.
- To explore the protective role of the skeletonization technique in mitigating sternal wound infections in BITA recipients.
Main Methods:
- Literature review of studies on BITA grafting in CABG.
- Analysis of data on long-term survival outcomes.
- Evaluation of research on sternal wound infection rates and risk factors.
- Review of studies investigating the skeletonization technique for arterial harvest.
Main Results:
- BITA grafting demonstrates a significant long-term survival advantage compared to single arterial grafts.
- The use of BITA is associated with an increased risk of sternal wound complications.
- Harvesting the internal thoracic artery using the skeletonization technique appears to reduce the incidence of sternal wound infections.
Conclusions:
- BITA grafting is an underutilized technique with proven long-term survival benefits.
- Careful consideration of sternal wound complications is necessary when planning BITA grafting.
- The skeletonization technique may be a valuable strategy to enhance the safety of BITA grafting by reducing infection risk.
Abstract:
Substantial evidence exists to support a long-term survival benefit with bilateral internal thoracic artery (BITA) revascularization in coronary artery bypass grafting. However, this technique remains grossly underutilized worldwide and especially in the United States. In this review, we discuss evidence for the advantages of BITA grafting as well as the associated the risk of sternal wound complications. We then review a growing body of literature that suggests 'skeletonization' of the internal thoracic artery during harvest confers a protective benefit against sternal wound infection in patients receiving BITA.
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