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Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Related Experiment Video

Updated: Apr 30, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Breast Reconstruction After Radiotherapy.

Hiroshi Yoshimoto1, Rodrigo Hamuy1

  • 1Department of Plastic and Reconstructive Surgery, Nagasaki University Hospital , Nagasaki City, Japan .

Advances in Wound Care
|April 25, 2014
PubMed
Summary

Breast cancer surgery has evolved from mastectomy to breast-conserving procedures. Optimal breast reconstruction methods, like autologous tissue transfer, are crucial, especially after radiotherapy, to minimize complications.

Area of Science:

  • Oncology
  • Plastic and Reconstructive Surgery

Background:

  • Historically, total mastectomy and axillary lymph node dissection were standard for breast cancer.
  • Breast-conserving surgery, combined with multidisciplinary treatments, is now prevalent, necessitating refined reconstructive techniques.

Purpose of the Study:

  • To discuss optimal breast reconstruction methods following breast cancer treatment, considering reduced excision ranges and radiation effects.
  • To compare autologous tissue reconstruction with implant-based methods, particularly in the context of radiotherapy.

Main Methods:

  • Review of current breast reconstruction techniques, including autologous flap transfer and autologous fat transfer.
  • Analysis of complications associated with implant-based reconstruction after radiotherapy.
  • Exploration of adipose-derived regenerative cells in autologous fat transfer for tissue repair.

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Main Results:

  • Breast reconstruction with implants has increased complication rates (infection, necrosis, exposure) post-radiotherapy.
  • Autologous tissue reconstruction, particularly flap transfer, is preferred when radiotherapy is involved.
  • Autologous fat transfer shows promise for repair and regeneration in reconstructive surgery.

Conclusions:

  • Autologous tissue reconstruction is the preferred method for breast reconstruction after radiotherapy.
  • Autologous fat transfer with regenerative cells is an emerging technique for breast reconstruction.
  • Choosing appropriate reconstructive methods is vital for successful outcomes in breast cancer treatment.