Related Experiment Videos
Helper T-cell determinants in vaccine design
1Department of Virology, Wellcome Biotechnology, Beckenham, Kent, UK.
Mice belonging to the H-2d haplotype do not respond to the 141-160 peptide of foot-and-mouth disease virus protein VP1. However, when defined 'foreign' helper T-cell determinants from ovalbumin or sperm whale myoglobin are added they do respond. These observations are likely to have important implications for the design of peptide vaccines.
Mice belonging to the H-2d haplotype do not respond to the 141-160 peptide of foot-and-mouth disease virus protein VP1. However, when defined 'foreign' helper T-cell determinants from ovalbumin or sperm whale myoglobin are added they do respond. These observations are likely to have important implications for the design of peptide vaccines.