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Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization
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Enzymatic preparation of a redox-responsive hydrogel for encapsulating and releasing living cells
Kousuke Moriyama1, Kosuke Minamihata, Rie Wakabayashi
1Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka 819-0395, Japan. nori_kamiya@mail.cstm.kyushu-u.ac.jp.
Chemical Communications (Cambridge, England)
|April 25, 2014
Abstract:
Horseradish peroxidase-mediated oxidative cross-linking of a thiolated poly(ethylene glycol) is promoted in the absence of exogenous hydrogen peroxide, by adding a small amount of a phenolic compound under physiological conditions. The prepared hydrogel can encapsulate and release living mammalian cells.
