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Management of pediatric delirium in critical illness: a practical update
S G Van Tuijl1, Y J Van Cauteren, T Pikhard
1Division Child and Adolescent Psychiatry, Department of Psychiatry and Psychology, Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands - jan.schieveld@mumc.nl.
Insights
Pediatric delirium (PD) is a critical brain dysfunction in the pediatric intensive care unit (PICU). This review offers an update on its diagnosis and management, including pharmacological and non-pharmacological treatments.
Area of Science:
- Critical Care Medicine
- Pediatric Neurology
- Neuroscience
Background:
- Pediatric delirium (PD) is an acute brain dysfunction frequently observed in pediatric intensive care units (PICUs).
- There is increasing recognition of its significant clinical and interdisciplinary importance.
- PD represents a specific manifestation of acute emotional and/or behavioral disturbances in children.
Purpose of the Study:
- To describe the three clinical presentations of pediatric delirium.
- To evaluate the differential diagnosis for PD in the PICU setting.
- To provide a practical update on pharmacological and non-pharmacological treatments for PD based on current literature and expert consensus.
Main Methods:
- Literature review of recent studies and expert opinions on pediatric delirium.
- Analysis of clinical presentations and differential diagnoses.
- Development of an interdisciplinary flowchart for diagnosis and management.
Main Results:
- Detailed description of the three main clinical presentations of PD.
- Evaluation of key differential diagnoses to distinguish PD from other conditions.
- Concise update on evidence-based pharmacological and non-pharmacological treatment strategies.
Conclusions:
- Effective management of PD requires an interdisciplinary approach.
- The provided flowchart aids in diagnosing and managing acute behavioral disturbances, with PD as a focus.
- This review serves as a practical guide for clinicians managing PD in the PICU.
Abstract:
Pediatric delirium (PD) is an acute state of brain dysfunction and is often seen in the pediatric intensive care unit (PICU). There is a growing awareness of its clinical interdisciplinary importance. The aim of this article was to describe the three clinical presentations, to evaluate the differential diagnosis and to give a concise and practical update for the pharmacological and non-pharmacological treatment of PD at the PICU, based on recent literature and expert opinions. We discuss an interdisciplinary flow chart which helps the reader dealing with the diagnosis and management of any acute emotional and or behavioral disturbance, of which PD is a special case.
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