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Mediolateral subchondral tibial bone mineral density difference does not predict osteoarthritis progression
Orthopedics
|April 26, 2014
Summary
This study found no link between the difference in bone mineral density (BMD) between the medial and lateral sides of the tibia and the progression of knee osteoarthritis in women over two years.
Area of Science:
- Orthopedics
- Rheumatology
- Radiology
Background:
- Conflicting data exist on the relationship between osteoporosis and osteoarthritis.
- Few studies have examined localized bone mineral density (BMD) of the knee in relation to osteoarthritis progression.
Purpose of the Study:
- To investigate if the mediolateral difference in proximal tibial bone mineral density (BMD) predicts knee osteoarthritis progression.
- To explore the association between tibial BMD asymmetry and subsequent joint degeneration.
Main Methods:
- Prospective study of 246 female volunteers over 2 years.
- Baseline measurement of proximal tibial BMD and calculation of mediolateral BMD ratio.
- Classification of osteoarthritis progression using Kellgren-Lawrence criteria at follow-up.
Main Results:
- No significant difference in the mean mediolateral BMD ratio was observed between osteoarthritis progressors (1.02) and non-progressors (1.01).
- The data indicate no association between proximal tibial BMD ratio and knee osteoarthritis progression.
Conclusions:
- The mediolateral difference in proximal tibial bone mineral density does not appear to be a predictor of knee osteoarthritis progression.
- Further research may be needed to clarify the complex relationship between bone density and joint degeneration.
