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Updated: Apr 30, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Blood transfusion sampling and a greater role for error recovery
1Transfusion Practitioner, NHS Lothian and Member, Better Blood Transfusion team, NHS National Services Scotland.
Patient identification errors in pre-transfusion blood sampling, known as "wrong blood in tube" events, persist despite safety measures. Enhanced error recovery strategies, alongside prevention, may improve patient safety.
Area of Science:
- Transfusion Medicine
- Patient Safety
- Healthcare Quality Improvement
Background:
- Patient identification errors during pre-transfusion blood sampling ('wrong blood in tube') pose significant risks, potentially leading to severe complications.
- Existing error prevention strategies have not fully resolved 'wrong blood in tube' incidents, necessitating a re-evaluation of the issue.
Purpose of the Study:
- To explore and understand the contributing factors of transfusion sampling errors.
- To serve as a foundation for examining current and potential error reduction approaches.
Main Methods:
- A comprehensive literature search was conducted to identify recurring themes related to transfusion sampling errors.
- The review focused on understanding the root causes and potential mitigation strategies for these errors.
Main Results:
- Human error remains a consistent factor across the multifaceted causes of transfusion sampling errors.
- Current error prevention efforts could be strengthened by incorporating a greater emphasis on error recovery mechanisms.
Conclusions:
- Developing methods for clinical staff to identify their own sampling errors is proposed.
- This approach aims to supplement existing patient safety initiatives in transfusion medicine.
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