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Updated: Apr 30, 2026

Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
Indoor particulate matter and secondhand smoke: simulation of an exposure scenario
C Protano1, M S Cattaruzza1, J F Osborn1
1Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.
Background:
To evaluate secondhand smoke (SHS) contribution on indoor Particulate Matter (PM) concentrations due to a single smoked cigarette in a real exposure scenario.
Methods:
Total Suspended Particles (TSP) and sizes ≤10 (PM(10)), ≤4 (PM(4)), ≤2.5 (PM(2.5)), and ≤1 μm (PM(1)) levels were measured before, during and after smoking in an enclosed smoke-free environment. The measurement was stopped 30 minutes after extinguishing the cigarette, to focus the monitoring just on SHS.
Results:
PM(1) concentrations dramatically increased during and 30 minutes after smoking (mean values: 21.1, 1544.0 and 279.0 μg/m3 before, during and after, respectively), while the other PM fractions remained almost unchanged.
Conclusions:
This experiment implies that smoking even one cigarette produces important indoor air pollution which may considerably increase individual exposure to ultrafine particles, and, consequently, pose a serious threat to health.
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