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Structure of the bovine eye lens gamma s-crystallin gene (formerly beta s)
G L van Rens1, J M Raats, H P Driessen
1Department of Biochemistry, University of Nijmegen, The Netherlands.
Gene
|May 30, 1989
Abstract:
The organization of a number of crystallin genes has already been resolved. One of the remaining genes of which the structure was hitherto unknown is the gamma s gene (formerly beta s). We determined the complete sequence of the bovine gamma s-crystallin-coding gene, apart from the middle region of the first intron. Since it contains three exons and two introns, we conclude that the former beta s, also at the gene level is gamma-crystallin-like. However, it is located on chromosome 3, in contrast to other gamma genes which occur in tandem on the human chromosome 2.