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Histopathologists' approach to keratoacanthoma: a multisite survey of regional variation in Great Britain and Ireland
Richard A Carr1, Joseph P Houghton2
1Department of Histopathology, Warwick Hospital, Warwick, UK.
Introduction:
This survey examines regional variation in the diagnosis of keratoacanthoma (KA).
Methods:
Twenty-three departments from Great Britain and Ireland were invited. The number of cases coded as KA or cutaneous SCC in the previous 12 months was retrieved. An SCC: KA ratio was calculated. Participants also provided free text responses.
Results:
Seventeen departments replied. A total of 11,718 cases were included with a breakdown of 998 KA and 10,720 SCC. The mean SCC:KA ratio was 10.7:1, range (2.5:1 to 139:1). Free text responses are presented.
Discussions:
An extreme variation in approach is highlighted by this survey. We believe a multidisciplinary team approach to the diagnosis of KA is essential. There seems to be a need for a carefully considered clinicopathological study, backed up by molecular studies, to better understand the natural biology of this diagnosis.
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