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Related Concept Videos

Diazonium Group Substitution: –OH and –H01:19

Diazonium Group Substitution: –OH and –H

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Nitrous acid, a weak acid, is prepared in situ via the reaction of sodium nitrite with a strong acid under cold conditions. This nitrous acid prepared in situ reacts with primary arylamines to form arenediazonium salts. Such reactions are known as diazotization reactions. As shown in Figure 1, the formation of arenediazonium salts begins with the decomposition of nitrous acid in an acidic solution to give nitrosonium ions.
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Nomenclature of Carboxylic Acid Derivatives: Amides and Nitriles01:11

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Naming Amides
The IUPAC and common names of amides are derived from the parent carboxylic acid, by replacing the suffix “oic acid” and “ic acid,” respectively, with “amide.” In the following example, the IUPAC name ethanamide is derived from ethanoic acid, and the common name, acetamide, is obtained from acetic acid.
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Preparation of Epoxides03:00

Preparation of Epoxides

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Overview
Epoxides result from alkene oxidation, which can be achieved by a) air, b) peroxy acids, c) hypochlorous acids, and d) halohydrin cyclization.
Epoxidation with Peroxy Acids
Epoxidation of alkenes via oxidation with peroxy acids involves the conversion of a carbon–carbon double bond to an epoxide using the oxidizing agent meta-chloroperoxybenzoic acid, commonly known as MCPBA. Since the O–O bond of peroxy acids is very weak, the addition of electrophilic oxygen of peroxy...
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Alkylation of β-Diester Enolates: Malonic Ester Synthesis01:14

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Malonic ester synthesis is a method to obtain α substituted carboxylic acids from ꞵ-diesters such as diethyl malonate and alkyl halides.
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Carboxylic Acids to Methylesters: Alkylation using Diazomethane01:33

Carboxylic Acids to Methylesters: Alkylation using Diazomethane

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Carboxylic acids react with diazomethane in an ether solvent via alkylation at the carboxylate oxygen atom to give methyl esters of the corresponding acid with excellent yields.
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Dehydration of Aldols to Enones: Acid-Catalyzed Aldol Condensation00:43

Dehydration of Aldols to Enones: Acid-Catalyzed Aldol Condensation

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As shown in Figure 1, under acidic conditions, the β-hydroxy ketone undergoes dehydration via an E1 elimination reaction to form an enone.
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Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
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Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

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(E)-N'-[4-(Di-methyl-amino)-benzyl-idene]-2-(4-methyl-phen-oxy)acetohydrazide.

M K Usha1, S Madan Kumar1, Nitinchandra2

  • 1Department of Studies in Physics, University of Mysore, Manasagangotri, Mysore 570 006, India.

Acta Crystallographica. Section E, Structure Reports Online
|April 26, 2014
PubMed
Summary

This study details the crystal structure of a novel organic compound, C18H21N3O2. The research highlights the molecule's three-dimensional supramolecular architecture formed through various hydrogen and weak π-contacts.

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Area of Science:

  • Crystallography
  • Supramolecular Chemistry
  • Organic Chemistry

Background:

  • Understanding molecular interactions is crucial in materials science.
  • Crystal engineering aims to design materials with specific properties.
  • Supramolecular chemistry explores non-covalent interactions in molecular assembly.

Purpose of the Study:

  • To determine the crystal structure of the title compound C18H21N3O2.
  • To analyze the intermolecular interactions governing the crystal packing.
  • To elucidate the supramolecular architecture formed by the compound.

Main Methods:

  • Single-crystal X-ray diffraction was employed to analyze the crystal structure.
  • Analysis of hydrogen bonds (C-H⋯O, N-H⋯O) and C-H⋯π interactions.
  • Geometric analysis of the dihedral angle between benzene rings.

Main Results:

  • The crystal structure of C18H21N3O2 was successfully determined.
  • A significant dihedral angle of 68.85° between the benzene rings was observed.
  • A 3D supramolecular network was formed via C-H⋯O, N-H⋯O hydrogen bonds, and C-H⋯π contacts.

Conclusions:

  • The title compound exhibits a defined dihedral angle between its aromatic rings.
  • Intermolecular forces dictate a robust 3D supramolecular assembly.
  • The findings contribute to the understanding of crystal packing in organic molecules.