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Updated: Apr 30, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
rac-2-Phenyl-1-[(2,4,6-triiso-propyl-benzene)-sulfon-yl]aziridine
Christopher Golz1, Hans Preut1, Carsten Strohmann1
1Fakultät für Chemie und Chemische Biologie, Technische Universität Dortmund, Otto-Hahn-Strasse 6, 44221 Dortmund, Germany.
Abstract:
In the title compound, C23H31NO2S, the geometry of the triiso-propyl-phenyl group is slightly distorted, with elongated C-C bonds at the ipso-C atom, and an S atom which deviates from the benzene ring plane by 0.228 (2) Å. This distortion is caused by the bulky substituents and, in comparison, an unbent geometry is observed in N-toluene-sulfonyl-aziridine [Zhu et al. (2006 ▶). Acta Cryst. E62, o1507-o1508]. π-π inter-actions between adjacent benzene rings [centroid-centroid distance = 3.7928 (11) Å] and are observed.
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