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Updated: Apr 30, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
5-Imino-3,4-diphenyl-1H-pyrrol-2-one
Evgeny Bulatov1, Tatiana Chulkova2, Matti Haukka3
1Department of Chemistry, Saint Petersburg State University, Universitetsky Pr. 26, 198504 Stary Petergof, Russian Federation ; Department of Chemistry, University of Jyvaskyla, PO Box 35 FI-40014 Jyväskylä, Finland.
Abstract:
The title compound, C16H12N2O, exists in the crystalline state as the 5-imino-3,4-di-phenyl--1H-pyrrol-2-one tautomer. The dihedral angles between the pyrrole and phenyl rings are 35.3 (2) and 55.3 (2)°. In the crystal, inversion dimers linked by pairs of N-H⋯N hydrogen bonds generate a graph-set motif of R 2 (2)(8) via N-H⋯N hydrogen bonds.
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