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Updated: Apr 30, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
N-(4-Meth-oxy-benzo-yl)-2-methyl-benzene-sulfonamide
S Sreenivasa1, B S Palakshamurthy2, S Madankumar3
1Department of Studies and Research in Chemistry, Tumkur University, Tumkur, Karnataka 572 103, India.
Abstract:
In the title compound, C15H15NO4S, the dihedral angle between the aromatic rings is 80.81 (1)° and the dihedral angle between the planes defined by the S-N-C=O fragment and the sulfonyl benzene ring is 86.34 (1)°. In the extended structure, dimers related by a crystallographic twofold axis are connected by pairs of both N-H⋯O hydrogen bonds and C-H⋯O inter-actions, which generate R 2 (2)(8) and R 2 (2)(14) loops, respectively. A weak aromatic π-π stacking inter-action is also observed [centroid-centroid separation = 3.7305 (3) Å].
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