Kawasaki disease: giant aneurysm with a large thrombus of the left coronary artery
Alakananda Ghosh1, Brojendra N Agarwala2
1Department of Emergency medicine, Rabindra Nth Tagore Hospital, Kolkata, India;
Clinics and Practice
|April 26, 2014
Insights
A febrile infant
Area of Science:
- Pediatrics
- Cardiology
- Infectious Diseases
Background:
- Kawasaki disease (KD) is a pediatric vasculitis affecting medium-sized arteries, primarily the coronary arteries.
- KD typically presents with prolonged fever and characteristic clinical signs, but atypical presentations occur.
Observation:
- A six-month-old infant presented with fever and stridor, an uncommon initial symptom for KD.
- The infant later developed classic signs of Kawasaki disease, including a giant coronary artery aneurysm with thrombosis.
Findings:
- Aggressive anticoagulation therapy successfully resolved the coronary artery thrombosis.
- Despite treatment, the giant coronary artery aneurysm persisted one year post-diagnosis.
Implications:
- Stridor can be an unusual presenting symptom of Kawasaki disease in infants.
- Giant coronary aneurysms may require long-term monitoring even after successful thrombosis treatment.
Abstract:
We report a six-month-old febrile infant presenting with stridor. Later on, he developed typical Kawasaki disease with giant aneurysm of the coronary artery with thrombosis that resolved with an aggressive anticoagulation therapy. The giant aneurysm still persisted a year later. Respiratory illness with stridor is an unusual presentation of Kawasaki disease.
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