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Related Experiment Video

Updated: Apr 30, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
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Primary renal synovial sarcoma.

Girish D Bakhshi1, Arshad S Khan1, Aftab S Shaikh1

  • 1Department of Surgery and.

Clinics and Practice
|April 26, 2014
PubMed
Summary

Primary renal synovial sarcoma is a rare kidney cancer. Diagnosis requires immunohistochemistry, and this case highlights successful treatment with radiation therapy and a positive two-year follow-up.

Keywords:
renal tumorsynovial sarcoma.

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Area of Science:

  • Oncology
  • Pathology
  • Genetics

Background:

  • Primary renal sarcoma is a rare malignancy, accounting for only 1% of all kidney tumors.
  • Synovial sarcoma, typically a soft tissue tumor near large joints, is exceptionally rare in the kidney.
  • Primary renal synovial sarcoma presents a diagnostic challenge and carries a poor prognosis.

Observation:

  • A 33-year-old female presented with a renal tumor.
  • The tumor was surgically removed via radical nephrectomy.
  • Histopathology and genetic analysis confirmed primary renal synovial sarcoma.

Findings:

  • Diagnosis of primary renal synovial sarcoma necessitates immunohistochemistry.
  • This rare kidney tumor should be considered in differential diagnoses of sarcomatoid and spindle cell renal tumors.
  • The patient received radiation therapy post-surgery.

Implications:

  • Early and accurate diagnosis through immunohistochemistry is crucial for effective management of primary renal synovial sarcoma.
  • This case demonstrates a favorable outcome following radiation therapy for primary renal synovial sarcoma.
  • Further research into rare renal tumors like synovial sarcoma is warranted to improve patient prognosis.