Ascorbic acid: its role in immune system and chronic inflammation diseases

Area of Science:

• Biochemistry
• Immunology
• Molecular Biology

Background:

• Ascorbic acid (vitamin C) is a well-known antioxidant crucial for preventing scurvy.
• It acts as a co-substrate for enzymes and regulates gene expression via transcription factors.
• Chronic inflammation and immune system dysfunction are linked to numerous diseases.

Purpose of the Study:

• To summarize the key roles of ascorbic acid in immune system regulation and inflammatory processes.
• To highlight its potential applications in various medical fields.
• To propose future research directions for antioxidant therapies.

Main Methods:

• Literature review and synthesis of existing research on ascorbic acid's functions.
• Analysis of its involvement in immune responses and inflammatory pathways.
• Evaluation of its therapeutic potential in different disease contexts.

Main Results:

• Ascorbic acid demonstrates significant immunostimulant, anti-inflammatory, antiviral, and antibacterial properties.
• It plays a critical role in cellular defense mechanisms during stressful conditions.
• Its ability to regulate gene expression and enzyme activity is well-established.

Conclusions:

• Ascorbic acid is essential for immune system stimulation and managing inflammatory processes.
• It shows promise as an adjuvant therapy in immunology, toxicology, and radiobiology.
• Future research should explore novel combinations of antioxidants and therapeutic agents.