Knowledge and attitudes to personal genomics testing for complex diseases among Nigerians

Area of Science:

• Genomics
• Public Health
• Medical Genetics

Background:

• Examines knowledge and attitudes towards personal genomics testing for complex diseases in Nigeria.
• Investigates how demographics like gender, age, religion, and education influence these views.

Purpose of the Study:

• To assess the current understanding and perceptions of personal genomics testing among Nigerians.
• To identify factors affecting knowledge and attitudes toward genetic testing for complex diseases.

Main Methods:

• Qualitative data collection through eight Focused Group Discussions (FGDs) and twenty-seven Key Informant Interviews (KIIs).
• Recruitment of diverse participants including healthy individuals, those with complex diseases, healthcare professionals, and policymakers in the Federal Capital Territory.

Main Results:

• Initial limited knowledge of genomics testing among respondents, improving after explanation.
• Positive attitudes towards genomics tests, alongside concerns about direct-to-consumer testing, prenatal testing, and data disclosure.
• Culture and religion significantly impact perspectives on genetic testing, particularly when conflicting with beliefs.

Conclusions:

• Nigerians possess limited initial knowledge of genomics testing but demonstrate a supportive attitude towards its predictive use for complex diseases.
• Personal genomics testing for complex diseases is not yet a common practice in Nigeria.
• Understanding cultural and religious contexts is crucial for the implementation of genomics testing.